UCL Research Shows High-Dose Intensive Movement Programs May Support Progress Even 18 Months After Stroke

The Queen Square Upper Limb Neurorehabilitation Programme followed 224 chronic stroke participants and published findings in peer-reviewed literature.
Study Context
The Queen Square Upper Limb Neurorehabilitation Programme at University College London (UCL) delivered high-dose, intensive upper limb movement programs to 224 chronic stroke participants. The median time since stroke was 18 months, well past the period typically associated with meaningful neurological progress. Participants received 90 hours of structured intensive engagement over three weeks.
The Evidence
Participants at every baseline level demonstrated clinically meaningful progress. ARAT and Fugl-Meyer Upper Limb scores both improved significantly. These gains were sustained at a 6-month follow-up assessment. No predictor of non-response was identified across the participant group.
Key Finding
224 participants
All showing clinically meaningful progress at median 18 months post-stroke, with gains sustained at 6-month follow-up. (UCL Queen Square Programme)
What The Research Shows
- Median ARAT scores progressed from 18 to 27 at 6-month follow-up
- Fugl-Meyer Upper Limb scores progressed from 26 to 37, considered clinically significant
- No baseline level predicted a lack of response; every participant subgroup showed progress
- Progress was sustained 6 months after the program ended, not just immediately after treatment
What This May Mean For You
This research challenges the widely held assumption that meaningful progress after stroke is limited to the first few months. High-dose intensive movement engagement, the model NeuroAnimation is built on, may support progress regardless of time elapsed since stroke.